Endocrine Abstracts

Sodium benzoate (the food additive E211) is widely used as a preservative in the food and pharmaceutical industries. A direct correlation between sodium benzoate intake and the development of sensibilization, nephrotoxicity and hepatotoxicity, disorders of puberty, and genotoxicity has been established. However, the literature does not provide data on changes in morphometric parameters of parathyroid glands after long-term use of sodium benzoate. The aim of this work is to stu...

Aim to study the particularities changes of organometric parameters of rat’s adrenal glands after 60-day administration of sodium benzoate and justify possible correction of identified changes by application of mexidol.The study was conducted on 90 mature male rats with an initial weight of 200–210 g, which were divided into three groups: 1st group – control animals, 2nd group – rats that within 60 days daily intragastrically injected...